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Of microglia in adult neurogenesis

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Emerging roles of microglia cells in the regulation of adult neural stem cells

Of microglia in adult neurogenesis
Of microglia in adult neurogenesis
Of microglia in adult neurogenesis
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Neurogenesis function, location in the brain & how to increase neurogenesis

Adult hippocampal neurogenesis results in the formation of new neurons and is a process of brain plasticity involved in learning and memory. The proliferation of adult neural stem or progenitor cells is regulated by several extrinsic factors such as experience, disease or aging and intrinsic factors originating from the neurogenic niche. Microglia is very abundant in the dentate gyrus DG and increasing evidence indicates that these cells mediate the inflammation-induced reduction in neurogenesis. However, the role of microglia in neurogenesis in physiological conditions remains poorly understood. In the mammalian brain, adult neural stem cells reside in the subventricular zone and subgranular zone SGZ of the hippocampus and continue to produce new neurons throughout life Altman, Adult neurogenesis has been observed in all mammalian species including humans Eriksson et al.
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A Distinct Population of Microglia Supports Adult Neurogenesis in the Subventricular Zone

Never-resting microglia: physiological roles in the healthy brain and pathological implications View all 16 Articles. Our view of microglia has dramatically changed in the last decade. In light of recent discoveries revealing a role of microglia as important effectors of neuronal circuit reorganization, considerable attention has been focused on how microglia and hippocampal neurogenesis could be an interdependent phenomenon.
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Correspondence Address: Dr. Universidad , Colima , Mexico. E-mail: osglez ucol. Recently, it has been identified that microglia cells regulate neuronal apoptosis during the early brain development and modulate synaptic function.
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